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Loss of In Vivo Replication Fitness of HIV-1 Variants Resistant to the Tat Inhibitor, dCA

HIV resistance to the Tat inhibitor didehydro-cortistatin A (dCA) in vitro correlates with higher levels of Tat-independent viral transcription and a seeming inability to enter latency, which rendered resistant isolates more susceptible to CTL-mediated immune clearance. Here, we investigated the abi...

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Detalles Bibliográficos
Autores principales:	Ling, Lijun, Leda, Ana R., Begum, Nurjahan, Spagnuolo, Rae Ann, Wahl, Angela, Garcia, J. Victor, Valente, Susana T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146675/ https://www.ncbi.nlm.nih.gov/pubmed/37112931 http://dx.doi.org/10.3390/v15040950

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