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ADME, Pharmacokinetic Scaling, Pharmacodynamic and Prediction of Human Dose and Regimen of Novel Antiviral Drugs

The search for new drugs is an extremely time-consuming and expensive endeavour. Much of that time and money go into generating predictive human pharmacokinetic profiles from preclinical efficacy and safety animal data. These pharmacokinetic profiles are used to prioritize or minimize the attrition...

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Detalles Bibliográficos
Autores principales:	Chaira, Tridib, Subramani, Chandru, Barman, Tarani Kanta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146820/ https://www.ncbi.nlm.nih.gov/pubmed/37111697 http://dx.doi.org/10.3390/pharmaceutics15041212

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