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TWIST2-mediated chromatin remodeling promotes fusion-negative rhabdomyosarcoma

Rhabdomyosarcoma (RMS) is a common soft tissue sarcoma in children that resembles developing skeletal muscle. Unlike normal muscle cells, RMS cells fail to differentiate despite expression of the myogenic determination protein MYOD. The TWIST2 transcription factor is frequently overexpressed in fusi...

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Detalles Bibliográficos
Autores principales: Shah, Akansha M., Guo, Lei, Morales, Maria Gabriela, Jaichander, Priscilla, Chen, Kenian, Huang, Huocong, Cano Hernandez, Karla, Xu, Lin, Bassel-Duby, Rhonda, Olson, Eric N., Liu, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146891/
https://www.ncbi.nlm.nih.gov/pubmed/37115930
http://dx.doi.org/10.1126/sciadv.ade8184

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