Regulation of Cell Proliferation and Nrf2-Mediated Antioxidant Defense: Conservation of Keap1 Cysteines and Nrf2 Binding Site in the Context of the Evolution of KLHL Family

Keap1 (Kelch-like ECH-associated protein 1) is one of the major negative regulators of the transcription factor Nrf2 (nuclear factor erythroid-2-related factor 2), which induces the expression of numerous proteins defending the cell against different stress conditions. Keap1 is generally negatively...

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Detalles Bibliográficos
Autores principales: Shilovsky, Gregory A., Dibrova, Daria V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146909/
https://www.ncbi.nlm.nih.gov/pubmed/37109574
http://dx.doi.org/10.3390/life13041045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146909/
https://www.ncbi.nlm.nih.gov/pubmed/37109574
http://dx.doi.org/10.3390/life13041045

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