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Treatment of Diet-Induced Obese Rats with CB(2) Agonist AM1241 or CB(2) Antagonist AM630 Reduces Leptin and Alters Thermogenic mRNA in Adipose Tissue

Diet-induced obesity (DIO) is a contributor to co-morbidities, resulting in alterations in hormones, lipids, and low-grade inflammation, with the cannabinoid type 2 receptor (CB(2)) contributing to the inflammatory response. The effects of modulating CB(2) with pharmacological treatments on inflamma...

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Detalles Bibliográficos
Autores principales: O’Keefe, Lannie, Vu, Teresa, Simcocks, Anna C., Jenkin, Kayte A., Mathai, Michael L., McAinch, Andrew J., Hutchinson, Dana S., Hryciw, Deanne H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147021/
https://www.ncbi.nlm.nih.gov/pubmed/37108770
http://dx.doi.org/10.3390/ijms24087601