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Human Salivary Histatin-1 Attenuates Osteoarthritis through Promoting M1/M2 Macrophage Transition

Osteoarthritis (OA) is an inflammation-driven degenerative joint disease. Human salivary peptide histatin-1 (Hst1) shows pro-healing and immunomodulatory properties. but its role in OA treatment is not fully understood. In this study, we investigated the efficacy of Hst1 in the inflammation modulati...

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Detalles Bibliográficos
Autores principales: Wu, Antong, Pathak, Janak Lal., Li, Xingyang, Cao, Wei, Zhong, Wenchao, Zhu, Mingjing, Wu, Qiuyu, Chen, Wanyi, Han, Qiao, Jiang, Siqing, Hei, Yuzhuo, Zhang, Ziyi, Wu, Gang, Zhang, Qingbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147060/
https://www.ncbi.nlm.nih.gov/pubmed/37111757
http://dx.doi.org/10.3390/pharmaceutics15041272