Giant Colloid Cyst: A Rare Etiology for Chronic Headache

Chronic headache affects a significant proportion of the population and can be caused by an underlying lesion or a serious condition. This case report describes a 38-year-old male with a history of chronic migraine headaches who presented with syncope. The patient was found to have bilateral papilledema on fundoscopic examination and a well-circumscribed, oval-shaped lesion located within the intraventricular septum on MRI. The lesion was identified as a colloid cyst and was surgically removed through endoscopic transnasal excision. The patient’s symptoms improved significantly postoperatively, including the resolution of his chronic headaches and syncope. This case report highlights the importance of considering space-occupying lesions as a possible cause of chronic headaches, particularly when symptoms do not respond to conventional treatments. It demonstrates that an endoscopic transnasal resection is a feasible approach, even for large colloid cysts.