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Roux-en-Y gastric bypass pouch outlet reduction using argon plasma coagulation to treat weight regain: a randomized controlled trial with a sham control group
Background and study aims A comparative study was conducted to evaluate the efficacy of argon plasma coagulation (APC) therapy in treating post Roux-en-Y gastric bypass (RYGB) weight regain and the incidence of complications related to this procedure, using a sham treatment group as a control. Pati...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Georg Thieme Verlag KG
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147510/ https://www.ncbi.nlm.nih.gov/pubmed/37124713 http://dx.doi.org/10.1055/a-2029-1845 |
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author | Fittipaldi-Fernandez, Ricardo José Zotarelli-Filho, Idiberto José de Santana, Marcelo Falcão Felicio de Lima, João Henrique Silva Bastos, Fernando Santos Barrichello-Junior, Sérgio Alexandre Teixeira dos Santos, Newton Guedes, Marcella Fittipaldi-Fernandez, Aline |
author_facet | Fittipaldi-Fernandez, Ricardo José Zotarelli-Filho, Idiberto José de Santana, Marcelo Falcão Felicio de Lima, João Henrique Silva Bastos, Fernando Santos Barrichello-Junior, Sérgio Alexandre Teixeira dos Santos, Newton Guedes, Marcella Fittipaldi-Fernandez, Aline |
author_sort | Fittipaldi-Fernandez, Ricardo José |
collection | PubMed |
description | Background and study aims A comparative study was conducted to evaluate the efficacy of argon plasma coagulation (APC) therapy in treating post Roux-en-Y gastric bypass (RYGB) weight regain and the incidence of complications related to this procedure, using a sham treatment group as a control. Patients and methods Forty-one patients with a minimum weight regain of 10 kg and a minimum postoperative time of 36 months were randomized into two groups. Results In the APC group (n = 21), the mean initial weight was 100.4 kg and the mean weight regain was 24.94 kg. In the sham group (n = 20), the mean initial weight was 103.65 kg, and the mean weight regain was 25.18 kg. Anastomotic stenosis occurred only after the first APC session. The results for the comparison of APC with the sham group showed a percentage weight regain loss of 63.95 compared to -.65, and weight loss of 15.02 and –0.57), percentage total weight loss of 14.46 and –0.62, excess weight loss of 54.32 % and –2.34 %), and BMI reduction of 5.38 and –0.21, with P < 0.0001 for all the comparisons. In the APC group, there was a significant reduction in HbA1c (5.66 % to 4.96 %) and triglycerides (153.20 mg/dL to 132.20 mg/dL). Conclusions This study indicates that APC outlet pouch reduction outperforms sham treatment in terms of weight loss for patients presenting weight regain after RYGB. |
format | Online Article Text |
id | pubmed-10147510 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Georg Thieme Verlag KG |
record_format | MEDLINE/PubMed |
spelling | pubmed-101475102023-04-29 Roux-en-Y gastric bypass pouch outlet reduction using argon plasma coagulation to treat weight regain: a randomized controlled trial with a sham control group Fittipaldi-Fernandez, Ricardo José Zotarelli-Filho, Idiberto José de Santana, Marcelo Falcão Felicio de Lima, João Henrique Silva Bastos, Fernando Santos Barrichello-Junior, Sérgio Alexandre Teixeira dos Santos, Newton Guedes, Marcella Fittipaldi-Fernandez, Aline Endosc Int Open Background and study aims A comparative study was conducted to evaluate the efficacy of argon plasma coagulation (APC) therapy in treating post Roux-en-Y gastric bypass (RYGB) weight regain and the incidence of complications related to this procedure, using a sham treatment group as a control. Patients and methods Forty-one patients with a minimum weight regain of 10 kg and a minimum postoperative time of 36 months were randomized into two groups. Results In the APC group (n = 21), the mean initial weight was 100.4 kg and the mean weight regain was 24.94 kg. In the sham group (n = 20), the mean initial weight was 103.65 kg, and the mean weight regain was 25.18 kg. Anastomotic stenosis occurred only after the first APC session. The results for the comparison of APC with the sham group showed a percentage weight regain loss of 63.95 compared to -.65, and weight loss of 15.02 and –0.57), percentage total weight loss of 14.46 and –0.62, excess weight loss of 54.32 % and –2.34 %), and BMI reduction of 5.38 and –0.21, with P < 0.0001 for all the comparisons. In the APC group, there was a significant reduction in HbA1c (5.66 % to 4.96 %) and triglycerides (153.20 mg/dL to 132.20 mg/dL). Conclusions This study indicates that APC outlet pouch reduction outperforms sham treatment in terms of weight loss for patients presenting weight regain after RYGB. Georg Thieme Verlag KG 2023-04-28 /pmc/articles/PMC10147510/ /pubmed/37124713 http://dx.doi.org/10.1055/a-2029-1845 Text en The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited. |
spellingShingle | Fittipaldi-Fernandez, Ricardo José Zotarelli-Filho, Idiberto José de Santana, Marcelo Falcão Felicio de Lima, João Henrique Silva Bastos, Fernando Santos Barrichello-Junior, Sérgio Alexandre Teixeira dos Santos, Newton Guedes, Marcella Fittipaldi-Fernandez, Aline Roux-en-Y gastric bypass pouch outlet reduction using argon plasma coagulation to treat weight regain: a randomized controlled trial with a sham control group |
title | Roux-en-Y gastric bypass pouch outlet reduction using argon plasma coagulation to treat weight regain: a randomized controlled trial with a sham control group |
title_full | Roux-en-Y gastric bypass pouch outlet reduction using argon plasma coagulation to treat weight regain: a randomized controlled trial with a sham control group |
title_fullStr | Roux-en-Y gastric bypass pouch outlet reduction using argon plasma coagulation to treat weight regain: a randomized controlled trial with a sham control group |
title_full_unstemmed | Roux-en-Y gastric bypass pouch outlet reduction using argon plasma coagulation to treat weight regain: a randomized controlled trial with a sham control group |
title_short | Roux-en-Y gastric bypass pouch outlet reduction using argon plasma coagulation to treat weight regain: a randomized controlled trial with a sham control group |
title_sort | roux-en-y gastric bypass pouch outlet reduction using argon plasma coagulation to treat weight regain: a randomized controlled trial with a sham control group |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147510/ https://www.ncbi.nlm.nih.gov/pubmed/37124713 http://dx.doi.org/10.1055/a-2029-1845 |
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