USP7 controls NGN3 stability and pancreatic endocrine lineage development

Understanding the factors and mechanisms involved in beta-cell development will guide therapeutic efforts to generate fully functional beta cells for diabetes. Neurogenin 3 (NGN3) is the key transcription factor that marks endocrine progenitors and drives beta-cell differentiation. Here we screen fo...

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Detalles Bibliográficos
Autores principales: Manea, Teodora, Nelson, Jessica Kristine, Garrone, Cristina Maria, Hansson, Karin, Evans, Ian, Behrens, Axel, Sancho, Rocio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147604/
https://www.ncbi.nlm.nih.gov/pubmed/37117185
http://dx.doi.org/10.1038/s41467-023-38146-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147604/
https://www.ncbi.nlm.nih.gov/pubmed/37117185
http://dx.doi.org/10.1038/s41467-023-38146-9

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