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USP7 controls NGN3 stability and pancreatic endocrine lineage development
Understanding the factors and mechanisms involved in beta-cell development will guide therapeutic efforts to generate fully functional beta cells for diabetes. Neurogenin 3 (NGN3) is the key transcription factor that marks endocrine progenitors and drives beta-cell differentiation. Here we screen fo...
Autores principales: | Manea, Teodora, Nelson, Jessica Kristine, Garrone, Cristina Maria, Hansson, Karin, Evans, Ian, Behrens, Axel, Sancho, Rocio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147604/ https://www.ncbi.nlm.nih.gov/pubmed/37117185 http://dx.doi.org/10.1038/s41467-023-38146-9 |
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