Structural basis for the ligand promiscuity of the neofunctionalized, carotenoid-binding fasciclin domain protein AstaP

Fasciclins (FAS1) are ancient adhesion protein domains with no common small ligand binding reported. A unique microalgal FAS1-containing astaxanthin (AXT)-binding protein (AstaP) binds a broad repertoire of carotenoids by a largely unknown mechanism. Here, we explain the ligand promiscuity of AstaP-...

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Detalles Bibliográficos
Autores principales: Kornilov, Fedor D., Slonimskiy, Yury B., Lunegova, Daria A., Egorkin, Nikita A., Savitskaya, Anna G., Kleymenov, Sergey Yu., Maksimov, Eugene G., Goncharuk, Sergey A., Mineev, Konstantin S., Sluchanko, Nikolai N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147662/
https://www.ncbi.nlm.nih.gov/pubmed/37117801
http://dx.doi.org/10.1038/s42003-023-04832-z

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