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A miR-124-mediated post-transcriptional mechanism controlling the cell fate switch of astrocytes to induced neurons

The microRNA (miRNA) miR-124 has been employed supplementary to neurogenic transcription factors (TFs) and other miRNAs to enhance direct neurogenic conversion. The aim of this study was to investigate whether miR-124 is sufficient to drive direct reprogramming of astrocytes to induced neurons (iNs)...

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Detalles Bibliográficos
Autores principales: Papadimitriou, Elsa, Koutsoudaki, Paraskevi N., Thanou, Irini, Karagkouni, Dimitra, Karamitros, Timokratis, Chroni-Tzartou, Dafni, Gaitanou, Maria, Gkemisis, Christos, Margariti, Maria, Xingi, Evangelia, Tzartos, Socrates J., Hatzigeorgiou, Artemis G., Thomaidou, Dimitra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147664/
https://www.ncbi.nlm.nih.gov/pubmed/36963393
http://dx.doi.org/10.1016/j.stemcr.2023.02.009