Cargando…

Gait improvement with wearable cyborg HAL trunk unit for parkinsonian patients: five case reports

Cybernic treatment involves the generation of an interactive bio-feedback loop between an individual’s nervous system and the worn cyborg Hybrid Assistive Limb (HAL); this treatment has been applied for several intractable neuromuscular disorders. Thus, it is of interest to determine its potential f...

Descripción completa

Detalles Bibliográficos
Autores principales: Uehara, Akira, Kawamoto, Hiroaki, Imai, Hisamasa, Shirai, Makoto, Sone, Masatomi, Noda, Sachiko, Sato, Shigeto, Hattori, Nobutaka, Sankai, Yoshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147720/
https://www.ncbi.nlm.nih.gov/pubmed/37117241
http://dx.doi.org/10.1038/s41598-023-33847-z
_version_ 1785034850813607936
author Uehara, Akira
Kawamoto, Hiroaki
Imai, Hisamasa
Shirai, Makoto
Sone, Masatomi
Noda, Sachiko
Sato, Shigeto
Hattori, Nobutaka
Sankai, Yoshiyuki
author_facet Uehara, Akira
Kawamoto, Hiroaki
Imai, Hisamasa
Shirai, Makoto
Sone, Masatomi
Noda, Sachiko
Sato, Shigeto
Hattori, Nobutaka
Sankai, Yoshiyuki
author_sort Uehara, Akira
collection PubMed
description Cybernic treatment involves the generation of an interactive bio-feedback loop between an individual’s nervous system and the worn cyborg Hybrid Assistive Limb (HAL); this treatment has been applied for several intractable neuromuscular disorders. Thus, it is of interest to determine its potential for parkinsonian patients. This study confirmed the feasibility of using a HAL trunk unit to improve parkinsonian gait disturbance. HAL establishes functional and physical synchronization with the wearer by providing lateral cyclic forces to the chest in the form of somatosensory and motor cues. To confirm the feasibility of its use for improving parkinsonian gait disturbances, we conducted experiments with three Parkinson’s disease patients and two patients with progressive supranuclear palsy. During the experiments, the immediate effect of the intervention was assessed; all participants exhibited improvements in gait disturbance while wearing the HAL unit, and this improvement effect persisted without the HAL unit in two participants. Afterward, based on the assessment, we conducted a continuous intervention for one participant. In this intervention, the number of steps in the final experiment was significantly decreased compared with the initial state. These findings suggest that the proposed method is an option for treating parkinsonian patients to generate somatosensory and motor cues.
format Online
Article
Text
id pubmed-10147720
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-101477202023-04-30 Gait improvement with wearable cyborg HAL trunk unit for parkinsonian patients: five case reports Uehara, Akira Kawamoto, Hiroaki Imai, Hisamasa Shirai, Makoto Sone, Masatomi Noda, Sachiko Sato, Shigeto Hattori, Nobutaka Sankai, Yoshiyuki Sci Rep Article Cybernic treatment involves the generation of an interactive bio-feedback loop between an individual’s nervous system and the worn cyborg Hybrid Assistive Limb (HAL); this treatment has been applied for several intractable neuromuscular disorders. Thus, it is of interest to determine its potential for parkinsonian patients. This study confirmed the feasibility of using a HAL trunk unit to improve parkinsonian gait disturbance. HAL establishes functional and physical synchronization with the wearer by providing lateral cyclic forces to the chest in the form of somatosensory and motor cues. To confirm the feasibility of its use for improving parkinsonian gait disturbances, we conducted experiments with three Parkinson’s disease patients and two patients with progressive supranuclear palsy. During the experiments, the immediate effect of the intervention was assessed; all participants exhibited improvements in gait disturbance while wearing the HAL unit, and this improvement effect persisted without the HAL unit in two participants. Afterward, based on the assessment, we conducted a continuous intervention for one participant. In this intervention, the number of steps in the final experiment was significantly decreased compared with the initial state. These findings suggest that the proposed method is an option for treating parkinsonian patients to generate somatosensory and motor cues. Nature Publishing Group UK 2023-04-28 /pmc/articles/PMC10147720/ /pubmed/37117241 http://dx.doi.org/10.1038/s41598-023-33847-z Text en © The Author(s) 2023, corrected publication 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Uehara, Akira
Kawamoto, Hiroaki
Imai, Hisamasa
Shirai, Makoto
Sone, Masatomi
Noda, Sachiko
Sato, Shigeto
Hattori, Nobutaka
Sankai, Yoshiyuki
Gait improvement with wearable cyborg HAL trunk unit for parkinsonian patients: five case reports
title Gait improvement with wearable cyborg HAL trunk unit for parkinsonian patients: five case reports
title_full Gait improvement with wearable cyborg HAL trunk unit for parkinsonian patients: five case reports
title_fullStr Gait improvement with wearable cyborg HAL trunk unit for parkinsonian patients: five case reports
title_full_unstemmed Gait improvement with wearable cyborg HAL trunk unit for parkinsonian patients: five case reports
title_short Gait improvement with wearable cyborg HAL trunk unit for parkinsonian patients: five case reports
title_sort gait improvement with wearable cyborg hal trunk unit for parkinsonian patients: five case reports
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147720/
https://www.ncbi.nlm.nih.gov/pubmed/37117241
http://dx.doi.org/10.1038/s41598-023-33847-z
work_keys_str_mv AT ueharaakira gaitimprovementwithwearablecyborghaltrunkunitforparkinsonianpatientsfivecasereports
AT kawamotohiroaki gaitimprovementwithwearablecyborghaltrunkunitforparkinsonianpatientsfivecasereports
AT imaihisamasa gaitimprovementwithwearablecyborghaltrunkunitforparkinsonianpatientsfivecasereports
AT shiraimakoto gaitimprovementwithwearablecyborghaltrunkunitforparkinsonianpatientsfivecasereports
AT sonemasatomi gaitimprovementwithwearablecyborghaltrunkunitforparkinsonianpatientsfivecasereports
AT nodasachiko gaitimprovementwithwearablecyborghaltrunkunitforparkinsonianpatientsfivecasereports
AT satoshigeto gaitimprovementwithwearablecyborghaltrunkunitforparkinsonianpatientsfivecasereports
AT hattorinobutaka gaitimprovementwithwearablecyborghaltrunkunitforparkinsonianpatientsfivecasereports
AT sankaiyoshiyuki gaitimprovementwithwearablecyborghaltrunkunitforparkinsonianpatientsfivecasereports