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Reproducibility and intratumoral heterogeneity of the PAM50 breast cancer assay
BACKGROUND: The PAM50 assay is used routinely in clinical practice to determine breast cancer prognosis and management; however, research assessing how technical variation and intratumoral heterogeneity contribute to misclassification and reproducibility of these tests is limited. METHODS: We evalua...
Autores principales: | Hurson, Amber N., Hamilton, Alina M., Olsson, Linnea T., Kirk, Erin L., Sherman, Mark E., Calhoun, Benjamin C., Geradts, Joseph, Troester, Melissa A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147733/ https://www.ncbi.nlm.nih.gov/pubmed/36892725 http://dx.doi.org/10.1007/s10549-023-06888-1 |
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