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BRAF inhibitors in BRAF V600E-mutated ameloblastoma: systematic review of rare cases in the literature
BACKGROUND: Ameloblastoma in 66% of the cases harbor a somatic mutation of the “mitogen-activated protein kinase” signaling pathway (BRAF V600E). In V600E mutations, BRAF is in the permanent “on” state and relays the growth-promoting signals independently of the EGFR pathway. Therefore, mutant BRAF...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147738/ https://www.ncbi.nlm.nih.gov/pubmed/37115331 http://dx.doi.org/10.1007/s12032-023-01993-z |