WNT7A suppresses adipogenesis of skeletal muscle mesenchymal stem cells and fatty infiltration through the alternative Wnt-Rho-YAP/TAZ signaling axis

Intramuscular fatty infiltration in muscle injuries and diseases, caused by aberrant adipogenesis of fibro-adipogenic progenitors, negatively impacts function. Intramuscular delivery of wingless-type MMTV integration site family 7a (WNT7A) offers a promising strategy to stimulate muscle regeneration...

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Detalles Bibliográficos
Autores principales: Fu, Chengcheng, Chin-Young, Britney, Park, GaYoung, Guzmán-Seda, Mariana, Laudier, Damien, Han, Woojin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147829/
https://www.ncbi.nlm.nih.gov/pubmed/37001514
http://dx.doi.org/10.1016/j.stemcr.2023.03.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147829/
https://www.ncbi.nlm.nih.gov/pubmed/37001514
http://dx.doi.org/10.1016/j.stemcr.2023.03.001

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