RAD-TGTs: high-throughput measurement of cellular mechanotype via rupture and delivery of DNA tension probes

Mechanical forces drive critical cellular processes that are reflected in mechanical phenotypes, or mechanotypes, of cells and their microenvironment. We present here “Rupture And Deliver” Tension Gauge Tethers (RAD-TGTs) in which flow cytometry is used to record the mechanical history of thousands...

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Detalles Bibliográficos
Autores principales: Pawlak, Matthew R., Smiley, Adam T., Ramirez, Maria Paz, Kelly, Marcus D., Shamsan, Ghaidan A., Anderson, Sarah M., Smeester, Branden A., Largaespada, David A., Odde, David J., Gordon, Wendy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147940/
https://www.ncbi.nlm.nih.gov/pubmed/37117218
http://dx.doi.org/10.1038/s41467-023-38157-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147940/
https://www.ncbi.nlm.nih.gov/pubmed/37117218
http://dx.doi.org/10.1038/s41467-023-38157-6

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