Cargando…
RAD-TGTs: high-throughput measurement of cellular mechanotype via rupture and delivery of DNA tension probes
Mechanical forces drive critical cellular processes that are reflected in mechanical phenotypes, or mechanotypes, of cells and their microenvironment. We present here “Rupture And Deliver” Tension Gauge Tethers (RAD-TGTs) in which flow cytometry is used to record the mechanical history of thousands...
Autores principales: | Pawlak, Matthew R., Smiley, Adam T., Ramirez, Maria Paz, Kelly, Marcus D., Shamsan, Ghaidan A., Anderson, Sarah M., Smeester, Branden A., Largaespada, David A., Odde, David J., Gordon, Wendy R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147940/ https://www.ncbi.nlm.nih.gov/pubmed/37117218 http://dx.doi.org/10.1038/s41467-023-38157-6 |
Ejemplares similares
-
Glioma Cell Migration Dynamics in Brain Tissue Assessed by Multimodal Optical Imaging
por: Liu, Chao J., et al.
Publicado: (2019) -
Screening cell mechanotype by parallel microfiltration
por: Qi, Dongping, et al.
Publicado: (2015) -
Slit-Robo GTPase-Activating Protein 2 as a metastasis suppressor in osteosarcoma
por: Marko, Tracy A., et al.
Publicado: (2016) -
Single Cell Mechanotype and Associated Molecular Changes in Urothelial Cell Transformation and Progression
por: Yu, Weibo, et al.
Publicado: (2020) -
Proteomic meta-study harmonization, mechanotyping and drug repurposing candidate prediction with ProHarMeD
por: Adamowicz, Klaudia, et al.
Publicado: (2023)