Oxytocin attenuates microglial activation and restores social and non-social memory in APP/PS1 Alzheimer model mice

Alzheimer’s disease (AD) is characterized by neurodegeneration, memory loss, and social withdrawal. Brain inflammation has emerged as a key pathogenic mechanism in AD. We hypothesized that oxytocin, a pro-social hypothalamic neuropeptide with anti-inflammatory properties, could have therapeutic acti...

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Detalles Bibliográficos
Autores principales: Selles, Maria Clara, Fortuna, Juliana T.S., de Faria, Yasmin P.R., Siqueira, Luciana Domett, Lima-Filho, Ricardo, Longo, Beatriz M., Froemke, Robert C., Chao, Moses V., Ferreira, Sergio T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148027/
https://www.ncbi.nlm.nih.gov/pubmed/37128547
http://dx.doi.org/10.1016/j.isci.2023.106545

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