Phenotypic Heterogeneity Analysis of APC-Mutant Colon Cancer by Proteomics and Phosphoproteomics Identifies RAI14 as a Key Prognostic Determinant in East Asians and Westerners

Adenomatous polyposis coli (APC) is an important tumor suppressor and is mostly linked to the regulation of the Wnt/β-catenin signaling pathway. APC mutation has been identified as an early event in more than 80% of sporadic colorectal cancers (CRCs). Moreover, prognostic differences are observed in...

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Detalles Bibliográficos
Autores principales: Zhang, Rou, Hu, Meng, Chen, Hai-Ning, Wang, Xiuxuan, Xia, Zhili, Liu, Yu, Wang, Rui, Xia, Xuyang, Shu, Yang, Du, Dan, Meng, Wenbo, Qi, Shiqian, Li, Yuan, Xu, Heng, Zhou, Zong-Guang, Dai, Lunzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article Collection: Cancer Proteomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148045/
https://www.ncbi.nlm.nih.gov/pubmed/36934880
http://dx.doi.org/10.1016/j.mcpro.2023.100532

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