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CryoEM reveals oligomeric isomers of a multienzyme complex and assembly mechanics

Propionyl-CoA carboxylase (PCC) is a multienzyme complex consisting of up to six α-subunits and six β-subunits. Belonging to a metabolic pathway converging on the citric acid cycle, it is present in most forms of life and irregularities in its assembly lead to serious illness in humans, known as pro...

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Detalles Bibliográficos
Autores principales: Lee, Jane K.J., Liu, Yun-Tao, Hu, Jason J., Aphasizheva, Inna, Aphasizhev, Ruslan, Zhou, Z. Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148081/
https://www.ncbi.nlm.nih.gov/pubmed/37128595
http://dx.doi.org/10.1016/j.yjsbx.2023.100088