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CryoEM reveals oligomeric isomers of a multienzyme complex and assembly mechanics
Propionyl-CoA carboxylase (PCC) is a multienzyme complex consisting of up to six α-subunits and six β-subunits. Belonging to a metabolic pathway converging on the citric acid cycle, it is present in most forms of life and irregularities in its assembly lead to serious illness in humans, known as pro...
Autores principales: | Lee, Jane K.J., Liu, Yun-Tao, Hu, Jason J., Aphasizheva, Inna, Aphasizhev, Ruslan, Zhou, Z. Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148081/ https://www.ncbi.nlm.nih.gov/pubmed/37128595 http://dx.doi.org/10.1016/j.yjsbx.2023.100088 |
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