miR-342-5p downstream to Notch enhances arterialization of endothelial cells in response to shear stress by repressing MYC

During vascular development, endothelial cells (ECs) undergo arterialization in response to genetic programs and shear stress-triggered mechanotransduction, forming a stable vasculature. Although the Notch receptor is known to sense shear stress and promote EC arterialization, its downstream mechani...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoyan, Sun, Jiaxing, Zhang, Peiran, Wen, Ting, Wang, Ruonan, Liang, Liang, Yang, Ziyan, Li, Jiayan, Zhang, Jiayulin, Che, Bo, Feng, Xingxing, Liu, Xiaowei, Han, Hua, Yan, Xianchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148082/
https://www.ncbi.nlm.nih.gov/pubmed/37128275
http://dx.doi.org/10.1016/j.omtn.2023.03.022

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