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APC-driven actin nucleation powers collective cell dynamics in colorectal cancer cells

Cell remodeling relies on dynamic rearrangements of cell contacts powered by the actin cytoskeleton. The tumor suppressor adenomatous polyposis coli (APC) nucleate actin filaments (F-actin) and localizes at cell junctions. Whether APC-driven actin nucleation acts in cell junction remodeling remains...

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Detalles Bibliográficos
Autores principales: Baro, Lautaro, Islam, Asifa, Brown, Hannah M., Bell, Zoë A., Juanes, M. Angeles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148130/
https://www.ncbi.nlm.nih.gov/pubmed/37128612
http://dx.doi.org/10.1016/j.isci.2023.106583