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Air pollution nanoparticle and alpha-synuclein fibrils synergistically decrease glutamate receptor A1, depending upon nPM batch activity

BACKGROUND: Epidemiological studies have variably linked air pollution to increased risk of Parkinson’s disease (PD). However, there is little experimental evidence for this association. Alpha-synuclein (α-syn) propagation plays central roles in PD and glutamate receptor A1 (GluA1) is involved in me...

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Detalles Bibliográficos
Autores principales: Zhang, Hongqiao, D'Agostino, Carla, Tulisiak, Christopher, Thorwald, Max A., Bergkvist, Liza, Lindquist, Allison, Meyerdirk, Lindsay, Schulz, Emily, Becker, Katelyn, Steiner, Jennifer A., Cacciottolo, Mafalda, Kwatra, Mohit, Rey, Nolwen L., Escobar Galvis, Martha L., Ma, Jiyan, Sioutas, Constantinos, Morgan, Todd E., Finch, Caleb E., Brundin, Patrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148131/
https://www.ncbi.nlm.nih.gov/pubmed/37128335
http://dx.doi.org/10.1016/j.heliyon.2023.e15622

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