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Gαs slow conformational transition upon GTP binding and a novel Gαs regulator

G proteins are major signaling partners for G protein-coupled receptors (GPCRs). Although stepwise structural changes during GPCR–G protein complex formation and guanosine diphosphate (GDP) release have been reported, no information is available with regard to guanosine triphosphate (GTP) binding. H...

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Detalles Bibliográficos
Autores principales: Ahn, Donghoon, Provasi, Davide, Duc, Nguyen Minh, Xu, Jun, Salas-Estrada, Leslie, Spasic, Aleksandar, Yun, Min Woo, Kang, Juyeong, Gim, Dongmin, Lee, Jaecheol, Du, Yang, Filizola, Marta, Chung, Ka Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148139/
https://www.ncbi.nlm.nih.gov/pubmed/37128611
http://dx.doi.org/10.1016/j.isci.2023.106603