Elevated expression of macrophage MERTK exhibits profibrotic effects and results in defective regulation of efferocytosis function in pulmonary fibrosis

Increased apoptosis of alveolar epithelial cells is a prominent feature of pulmonary fibrosis. Macrophage efferocytosis, phagocytosis of apoptotic cells by macrophages, is crucial for maintaining tissue homeostasis. Expression of Mer tyrosine kinase (MERTK, an important recognition receptor in effer...

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Detalles Bibliográficos
Autores principales: She, Yixin, Xu, Xin, Yu, Qingyang, Yang, Xiangsheng, He, Jianxing, Tang, Xiao Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148433/
https://www.ncbi.nlm.nih.gov/pubmed/37120511
http://dx.doi.org/10.1186/s12931-023-02424-3

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