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Risk factors of acute renal failure in patients with protective ileostomy after rectal cancer surgery

BACKGROUND: Despite the potential benefits of protective ileostomy in rectal surgery, diverting loop ileostomy construction is not free of specific medical consequences implying unplanned hospital readmissions. The most common reason for readmission in these patients is a dehydration with a prevalen...

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Autores principales: Omar, Marghich, Tarek, Anis, Abdeslam, Bouassria, Amouzou, Efoé-Ga Yawod Olivier, Abdelmalek, Ousadden, Khalid, Ait Taleb, Hicham, El Bouhaddouti, Ouadii, Mouaqit, Khalid, Mazaz, Amine, Rahili Mohamed, Bachir, Benjelloun El, Emmanuel, Benizri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148495/
https://www.ncbi.nlm.nih.gov/pubmed/37118719
http://dx.doi.org/10.1186/s12893-023-02016-4
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author Omar, Marghich
Tarek, Anis
Abdeslam, Bouassria
Amouzou, Efoé-Ga Yawod Olivier
Abdelmalek, Ousadden
Khalid, Ait Taleb
Hicham, El Bouhaddouti
Ouadii, Mouaqit
Khalid, Mazaz
Amine, Rahili Mohamed
Bachir, Benjelloun El
Emmanuel, Benizri
author_facet Omar, Marghich
Tarek, Anis
Abdeslam, Bouassria
Amouzou, Efoé-Ga Yawod Olivier
Abdelmalek, Ousadden
Khalid, Ait Taleb
Hicham, El Bouhaddouti
Ouadii, Mouaqit
Khalid, Mazaz
Amine, Rahili Mohamed
Bachir, Benjelloun El
Emmanuel, Benizri
author_sort Omar, Marghich
collection PubMed
description BACKGROUND: Despite the potential benefits of protective ileostomy in rectal surgery, diverting loop ileostomy construction is not free of specific medical consequences implying unplanned hospital readmissions. The most common reason for readmission in these patients is a dehydration with a prevalence of acute renal failure (ARF) of 20%. The objective of this study was to establish the predictive factors of ARF in patients with protective ileostomy after surgery for rectal cancer from a bicentric study. METHODS: we conducted a bicentric retrospective cohort study to identify the risk factor of ARF. This study was carried out on 277 patients operated for rectal cancer with necessity of a protective ileostomy during the study period. ARF was measured at any endpoint between ileostomy creation and reversal. Multiple logistic regressions were performed to identify independent risk factors. RESULTS: A total of 277 patients were included, and 18% (n = 50) were readmitted for ARF. In multivariate logistic regression, increased age (OR 1.02, p = 0.01), Psychiatric diseases (OR 4.33, p = 0.014), Angiotensin II receptor blockers (OR 5.15, p < 0.001) and the ASA score ≥ 3 (OR 9.5, p < 0.001) were significantly associated with ARF. CONCLUSION: Acute renal failure is a prevalent and significant event in the postoperative course of ileostomy patients. Patients at risk should be risk stratified before discharge and targeted for intensive preventive measures.
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spelling pubmed-101484952023-04-30 Risk factors of acute renal failure in patients with protective ileostomy after rectal cancer surgery Omar, Marghich Tarek, Anis Abdeslam, Bouassria Amouzou, Efoé-Ga Yawod Olivier Abdelmalek, Ousadden Khalid, Ait Taleb Hicham, El Bouhaddouti Ouadii, Mouaqit Khalid, Mazaz Amine, Rahili Mohamed Bachir, Benjelloun El Emmanuel, Benizri BMC Surg Research BACKGROUND: Despite the potential benefits of protective ileostomy in rectal surgery, diverting loop ileostomy construction is not free of specific medical consequences implying unplanned hospital readmissions. The most common reason for readmission in these patients is a dehydration with a prevalence of acute renal failure (ARF) of 20%. The objective of this study was to establish the predictive factors of ARF in patients with protective ileostomy after surgery for rectal cancer from a bicentric study. METHODS: we conducted a bicentric retrospective cohort study to identify the risk factor of ARF. This study was carried out on 277 patients operated for rectal cancer with necessity of a protective ileostomy during the study period. ARF was measured at any endpoint between ileostomy creation and reversal. Multiple logistic regressions were performed to identify independent risk factors. RESULTS: A total of 277 patients were included, and 18% (n = 50) were readmitted for ARF. In multivariate logistic regression, increased age (OR 1.02, p = 0.01), Psychiatric diseases (OR 4.33, p = 0.014), Angiotensin II receptor blockers (OR 5.15, p < 0.001) and the ASA score ≥ 3 (OR 9.5, p < 0.001) were significantly associated with ARF. CONCLUSION: Acute renal failure is a prevalent and significant event in the postoperative course of ileostomy patients. Patients at risk should be risk stratified before discharge and targeted for intensive preventive measures. BioMed Central 2023-04-28 /pmc/articles/PMC10148495/ /pubmed/37118719 http://dx.doi.org/10.1186/s12893-023-02016-4 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Omar, Marghich
Tarek, Anis
Abdeslam, Bouassria
Amouzou, Efoé-Ga Yawod Olivier
Abdelmalek, Ousadden
Khalid, Ait Taleb
Hicham, El Bouhaddouti
Ouadii, Mouaqit
Khalid, Mazaz
Amine, Rahili Mohamed
Bachir, Benjelloun El
Emmanuel, Benizri
Risk factors of acute renal failure in patients with protective ileostomy after rectal cancer surgery
title Risk factors of acute renal failure in patients with protective ileostomy after rectal cancer surgery
title_full Risk factors of acute renal failure in patients with protective ileostomy after rectal cancer surgery
title_fullStr Risk factors of acute renal failure in patients with protective ileostomy after rectal cancer surgery
title_full_unstemmed Risk factors of acute renal failure in patients with protective ileostomy after rectal cancer surgery
title_short Risk factors of acute renal failure in patients with protective ileostomy after rectal cancer surgery
title_sort risk factors of acute renal failure in patients with protective ileostomy after rectal cancer surgery
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148495/
https://www.ncbi.nlm.nih.gov/pubmed/37118719
http://dx.doi.org/10.1186/s12893-023-02016-4
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