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Hip fracture incidence and post-fracture mortality in Victoria, Australia: a state-wide cohort study

SUMMARY: Hip fractures are a major public health concern. Number of hip fractures cases increased by 20% from 2012 to 2018. Factors associated with post-fracture mortality included men, those who are frail, living in a non-metropolitan region, or residing in a residential aged care facility. Our res...

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Autores principales: Leung, Miriam T. Y., Marquina, Clara, Turner, Justin P., Ilomaki, Jenni, Tran, Tim, Bell, J. Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer London 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148778/
https://www.ncbi.nlm.nih.gov/pubmed/37119328
http://dx.doi.org/10.1007/s11657-023-01254-6
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author Leung, Miriam T. Y.
Marquina, Clara
Turner, Justin P.
Ilomaki, Jenni
Tran, Tim
Bell, J. Simon
author_facet Leung, Miriam T. Y.
Marquina, Clara
Turner, Justin P.
Ilomaki, Jenni
Tran, Tim
Bell, J. Simon
author_sort Leung, Miriam T. Y.
collection PubMed
description SUMMARY: Hip fractures are a major public health concern. Number of hip fractures cases increased by 20% from 2012 to 2018. Factors associated with post-fracture mortality included men, those who are frail, living in a non-metropolitan region, or residing in a residential aged care facility. Our results are useful for planning healthcare interventions. PURPOSE: Hip fractures are a major public health concern in Australia. Data on hip fracture incidence and mortality are needed to plan and evaluate healthcare interventions. The aims of the study were to investigate (1) the time-trend in absolute number and incidence of first hip fractures, and (2) factors associated with mortality following first hip fractures in Victoria, Australia. METHODS: A state-wide cohort study of all patients aged [Formula: see text] 50 years admitted to a Victorian hospital for first hip fracture between July 2012 and June 2018. Annual age-standardized incidence rates were calculated using population data from Australian Bureau of Statistics. Multivariate negative binomial regression was used to investigate factors associated with post-fracture mortality. RESULTS: Overall, 31,578 patients had a first hip fracture, of whom two-thirds were women and 47% were [Formula: see text] 85 years old. Absolute annual numbers of first hip fractures increased by 20%. There was no significant change in age- and sex-adjusted incidence. In total, 8% died within 30 days and 25% within 1 year. Factors associated with 30-day mortality included age (≥ 85 years old versus 50–64 years old, mortality rate ratio [MRR] 8.05, 95% confidence interval [CI] 5.86–11.33), men (MRR 2.11, 95% CI 1.88–2.37), higher Hospital Frailty Risk Scores (high frailty versus no frailty, MRR 3.46, 95% CI 2.66–4.50), admission from a residential aged care facility (RACF) (MRR 2.28, 95% CI 1.85–2.82), and residing in a non-metropolitan region (MRR 1.22, 95% CI 1.09–1.38). The same factors were associated with 1-year mortality. CONCLUSION: The absolute increase in hip fractures highlights the need for interventions to reduce fracture risk, especially for those at higher risk of post-fracture mortality, including men and those who are frail, living in a non-metropolitan region, or residing in a RACF. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s11657-023-01254-6.
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spelling pubmed-101487782023-05-01 Hip fracture incidence and post-fracture mortality in Victoria, Australia: a state-wide cohort study Leung, Miriam T. Y. Marquina, Clara Turner, Justin P. Ilomaki, Jenni Tran, Tim Bell, J. Simon Arch Osteoporos Original Article SUMMARY: Hip fractures are a major public health concern. Number of hip fractures cases increased by 20% from 2012 to 2018. Factors associated with post-fracture mortality included men, those who are frail, living in a non-metropolitan region, or residing in a residential aged care facility. Our results are useful for planning healthcare interventions. PURPOSE: Hip fractures are a major public health concern in Australia. Data on hip fracture incidence and mortality are needed to plan and evaluate healthcare interventions. The aims of the study were to investigate (1) the time-trend in absolute number and incidence of first hip fractures, and (2) factors associated with mortality following first hip fractures in Victoria, Australia. METHODS: A state-wide cohort study of all patients aged [Formula: see text] 50 years admitted to a Victorian hospital for first hip fracture between July 2012 and June 2018. Annual age-standardized incidence rates were calculated using population data from Australian Bureau of Statistics. Multivariate negative binomial regression was used to investigate factors associated with post-fracture mortality. RESULTS: Overall, 31,578 patients had a first hip fracture, of whom two-thirds were women and 47% were [Formula: see text] 85 years old. Absolute annual numbers of first hip fractures increased by 20%. There was no significant change in age- and sex-adjusted incidence. In total, 8% died within 30 days and 25% within 1 year. Factors associated with 30-day mortality included age (≥ 85 years old versus 50–64 years old, mortality rate ratio [MRR] 8.05, 95% confidence interval [CI] 5.86–11.33), men (MRR 2.11, 95% CI 1.88–2.37), higher Hospital Frailty Risk Scores (high frailty versus no frailty, MRR 3.46, 95% CI 2.66–4.50), admission from a residential aged care facility (RACF) (MRR 2.28, 95% CI 1.85–2.82), and residing in a non-metropolitan region (MRR 1.22, 95% CI 1.09–1.38). The same factors were associated with 1-year mortality. CONCLUSION: The absolute increase in hip fractures highlights the need for interventions to reduce fracture risk, especially for those at higher risk of post-fracture mortality, including men and those who are frail, living in a non-metropolitan region, or residing in a RACF. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s11657-023-01254-6. Springer London 2023-04-29 2023 /pmc/articles/PMC10148778/ /pubmed/37119328 http://dx.doi.org/10.1007/s11657-023-01254-6 Text en © The Author(s) 2023, corrected publication 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Leung, Miriam T. Y.
Marquina, Clara
Turner, Justin P.
Ilomaki, Jenni
Tran, Tim
Bell, J. Simon
Hip fracture incidence and post-fracture mortality in Victoria, Australia: a state-wide cohort study
title Hip fracture incidence and post-fracture mortality in Victoria, Australia: a state-wide cohort study
title_full Hip fracture incidence and post-fracture mortality in Victoria, Australia: a state-wide cohort study
title_fullStr Hip fracture incidence and post-fracture mortality in Victoria, Australia: a state-wide cohort study
title_full_unstemmed Hip fracture incidence and post-fracture mortality in Victoria, Australia: a state-wide cohort study
title_short Hip fracture incidence and post-fracture mortality in Victoria, Australia: a state-wide cohort study
title_sort hip fracture incidence and post-fracture mortality in victoria, australia: a state-wide cohort study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148778/
https://www.ncbi.nlm.nih.gov/pubmed/37119328
http://dx.doi.org/10.1007/s11657-023-01254-6
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