Piezo2 expressing nociceptors mediate mechanical sensitization in experimental osteoarthritis

Non-opioid targets are needed for addressing osteoarthritis pain, which is mechanical in nature and associated with daily activities such as walking and climbing stairs. Piezo2 has been implicated in the development of mechanical pain, but the mechanisms by which this occurs remain poorly understood...

Descripción completa

Detalles Bibliográficos
Autores principales: Obeidat, Alia M., Wood, Matthew J., Adamczyk, Natalie S., Ishihara, Shingo, Li, Jun, Wang, Lai, Ren, Dongjun, Bennett, David A., Miller, Richard J., Malfait, Anne-Marie, Miller, Rachel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148822/
https://www.ncbi.nlm.nih.gov/pubmed/37120427
http://dx.doi.org/10.1038/s41467-023-38241-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148822/
https://www.ncbi.nlm.nih.gov/pubmed/37120427
http://dx.doi.org/10.1038/s41467-023-38241-x

Ejemplares similares