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Piezo2 expressing nociceptors mediate mechanical sensitization in experimental osteoarthritis
Non-opioid targets are needed for addressing osteoarthritis pain, which is mechanical in nature and associated with daily activities such as walking and climbing stairs. Piezo2 has been implicated in the development of mechanical pain, but the mechanisms by which this occurs remain poorly understood...
Autores principales: | Obeidat, Alia M., Wood, Matthew J., Adamczyk, Natalie S., Ishihara, Shingo, Li, Jun, Wang, Lai, Ren, Dongjun, Bennett, David A., Miller, Richard J., Malfait, Anne-Marie, Miller, Rachel E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148822/ https://www.ncbi.nlm.nih.gov/pubmed/37120427 http://dx.doi.org/10.1038/s41467-023-38241-x |
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