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Content-based filter queries on DNA data storage systems

Recent developments in DNA data storage systems have revealed the great potential to store large amounts of data at a very high density with extremely long persistence and low cost. However, despite recent contributions to robust data encoding, current DNA storage systems offer limited support for r...

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Detalles Bibliográficos
Autores principales: El-Shaikh, Alex, Seeger, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148835/
https://www.ncbi.nlm.nih.gov/pubmed/37120614
http://dx.doi.org/10.1038/s41598-023-34160-5
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author El-Shaikh, Alex
Seeger, Bernhard
author_facet El-Shaikh, Alex
Seeger, Bernhard
author_sort El-Shaikh, Alex
collection PubMed
description Recent developments in DNA data storage systems have revealed the great potential to store large amounts of data at a very high density with extremely long persistence and low cost. However, despite recent contributions to robust data encoding, current DNA storage systems offer limited support for random access on DNA storage devices due to restrictive biochemical constraints. Moreover, state-of-the-art approaches do not support content-based filter queries on DNA storage. This paper introduces the first encoding for DNA that enables content-based searches on structured data like relational database tables. We provide the details of the methods for coding and decoding millions of directly accessible data objects on DNA. We evaluate the derived codes on real data sets and verify their robustness.
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spelling pubmed-101488352023-05-01 Content-based filter queries on DNA data storage systems El-Shaikh, Alex Seeger, Bernhard Sci Rep Article Recent developments in DNA data storage systems have revealed the great potential to store large amounts of data at a very high density with extremely long persistence and low cost. However, despite recent contributions to robust data encoding, current DNA storage systems offer limited support for random access on DNA storage devices due to restrictive biochemical constraints. Moreover, state-of-the-art approaches do not support content-based filter queries on DNA storage. This paper introduces the first encoding for DNA that enables content-based searches on structured data like relational database tables. We provide the details of the methods for coding and decoding millions of directly accessible data objects on DNA. We evaluate the derived codes on real data sets and verify their robustness. Nature Publishing Group UK 2023-04-29 /pmc/articles/PMC10148835/ /pubmed/37120614 http://dx.doi.org/10.1038/s41598-023-34160-5 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
El-Shaikh, Alex
Seeger, Bernhard
Content-based filter queries on DNA data storage systems
title Content-based filter queries on DNA data storage systems
title_full Content-based filter queries on DNA data storage systems
title_fullStr Content-based filter queries on DNA data storage systems
title_full_unstemmed Content-based filter queries on DNA data storage systems
title_short Content-based filter queries on DNA data storage systems
title_sort content-based filter queries on dna data storage systems
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148835/
https://www.ncbi.nlm.nih.gov/pubmed/37120614
http://dx.doi.org/10.1038/s41598-023-34160-5
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