mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin

mTOR complex 2 (mTORC2) has been implicated as a key regulator of glioblastoma cell migration. However, the roles of mTORC2 in the migrational control process have not been entirely elucidated. Here, we elaborate that active mTORC2 is crucial for GBM cell motility. Inhibition of mTORC2 impaired cell...

Descripción completa

Detalles Bibliográficos
Autores principales: Chantaravisoot, Naphat, Wongkongkathep, Piriya, Kalpongnukul, Nuttiya, Pacharakullanon, Narawit, Kaewsapsak, Pornchai, Ariyachet, Chaiyaboot, Loo, Joseph A., Tamanoi, Fuyuhiko, Pisitkun, Trairak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148843/
https://www.ncbi.nlm.nih.gov/pubmed/37120454
http://dx.doi.org/10.1038/s41598-023-33872-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148843/
https://www.ncbi.nlm.nih.gov/pubmed/37120454
http://dx.doi.org/10.1038/s41598-023-33872-y

Ejemplares similares