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PPAR-γ regulates the effector function of human T helper 9 cells by promoting glycolysis

T helper 9 (T(H)9) cells promote allergic tissue inflammation and express the type 2 cytokines, IL-9 and IL-13, as well as the transcription factor, PPAR-γ. However, the functional role of PPAR-γ in human T(H)9 cells remains unknown. Here, we demonstrate that PPAR-γ drives activation-induced glycoly...

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Detalles Bibliográficos
Autores principales:	Bertschi, Nicole L., Steck, Oliver, Luther, Fabian, Bazzini, Cecilia, von Meyenn, Leonhard, Schärli, Stefanie, Vallone, Angela, Felser, Andrea, Keller, Irene, Friedli, Olivier, Freigang, Stefan, Begré, Nadja, Radonjic-Hoesli, Susanne, Lamos, Cristina, Gabutti, Max Philip, Benzaquen, Michael, Laimer, Markus, Simon, Dagmar, Nuoffer, Jean-Marc, Schlapbach, Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148883/ https://www.ncbi.nlm.nih.gov/pubmed/37120582 http://dx.doi.org/10.1038/s41467-023-38233-x

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