OSMR deficiency aggravates pressure overload-induced cardiac hypertrophy by modulating macrophages and OSM/LIFR/STAT3 signalling

BACKGROUND: Oncostatin M (OSM) is a secreted cytokine of the interleukin (IL)-6 family that induces biological effects by activating functional receptor complexes of the common signal transducing component glycoprotein 130 (gp130) and OSM receptor β (OSMR) or leukaemia inhibitory factor receptor (LI...

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Detalles Bibliográficos
Autores principales: Feng, Yizhou, Yuan, Yuan, Xia, Hongxia, Wang, Zhaopeng, Che, Yan, Hu, Zhefu, Deng, Jiangyang, Li, Fangfang, Wu, Qingqing, Bian, Zhouyan, Zhou, Heng, Shen, Difei, Tang, Qizhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149029/
https://www.ncbi.nlm.nih.gov/pubmed/37120549
http://dx.doi.org/10.1186/s12967-023-04163-x

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