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A glucose-sensing mechanism with glucose transporter 1 and pyruvate kinase in the area postrema regulates hepatic glucose production in rats

The area postrema (AP) of the brain is exposed to circulating metabolites and hormones. However, whether AP detects glucose changes to exert biological responses remains unknown. Its neighboring nuclei, the nucleus tractus solitarius (NTS), responds to acute glucose infusion by inhibiting hepatic gl...

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Detalles Bibliográficos
Autores principales: Li, Rosa J.W., Chiu, Jennifer F.M., Bruce, Kyla, Zhang, Song-Yang, Barros, Daniel R., Yue, Jessica T.Y., Lam, Tony K.T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149203/
https://www.ncbi.nlm.nih.gov/pubmed/36963496
http://dx.doi.org/10.1016/j.jbc.2023.104633