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De Novo SCLC Transformation From KRAS G12C-Mutated Lung Adenocarcinoma With Excellent Response to Sotorasib: A Case Report

The transformation to SCLC is a known mechanism of resistance against molecularly targeted therapies. This study reports a patient with untreated lung adenocarcinoma, characterized by a KRAS G12C mutation, which transformed into SCLC before treatment. Both the adenocarcinoma and SCLC components were...

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Detalles Bibliográficos
Autores principales:	Ito, Takanori, Oi, Issei, Saito, Zentaro, Imakita, Takuma, Kanai, Osamu, Fujita, Kohei, Tachibana, Hiromasa, Moriyoshi, Koki, Mio, Tadashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149245/ https://www.ncbi.nlm.nih.gov/pubmed/37131995 http://dx.doi.org/10.1016/j.jtocrr.2023.100510

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