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Inhibition of phospholipase D1 ameliorates hepatocyte steatosis and non-alcoholic fatty liver disease

BACKGROUND & AIMS: Phospholipase D1 (PLD1), a phosphatidylcholine-hydrolysing enzyme, is involved in cellular lipid metabolism. However, its involvement in hepatocyte lipid metabolism and consequently non-alcoholic fatty liver disease (NAFLD) has not been explicitly explored. METHODS: NAFLD was...

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Detalles Bibliográficos
Autores principales: Wang, Huan, Zhao, Yushang, Pan, Yuhualei, Yang, Aiting, Li, Changying, Wang, Song, Dong, Zhao, Li, Mengyi, Wang, Songlin, Zhang, Zhongtao, Zhu, Yanbing, Zhang, Dong, Sun, Guangyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149370/
https://www.ncbi.nlm.nih.gov/pubmed/37138676
http://dx.doi.org/10.1016/j.jhepr.2023.100726