The establishment of mitotic errors-driven senescence depends on autophagy

We and others have reported that senescence onset is accompanied by genomic instability that is evident by several defects, such as aneuploidy or erroneous mitosis features. Here, we report that these defects also appear in young cells upon oxidative insult. We provide evidence that these errors cou...

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Detalles Bibliográficos
Autores principales: Goutas, Andreas, Outskouni, Zozo, Papathanasiou, Ioanna, Georgakopoulou, Aphrodite, Karpetas, Georgios E., Gonos, Efstathios S., Trachana, Varvara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149375/
https://www.ncbi.nlm.nih.gov/pubmed/37094517
http://dx.doi.org/10.1016/j.redox.2023.102701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149375/
https://www.ncbi.nlm.nih.gov/pubmed/37094517
http://dx.doi.org/10.1016/j.redox.2023.102701

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