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The deubiquitinase USP11 ameliorates intervertebral disc degeneration by regulating oxidative stress-induced ferroptosis via deubiquitinating and stabilizing Sirt3

Increasing studies have reported that intervertebral disc degeneration (IVDD) is the main contributor and independent risk factor for low back pain (LBP), it would be, therefore, enlightening that investigating the exact pathogenesis of IVDD and developing target-specific molecular drugs in the futu...

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Detalles Bibliográficos
Autores principales: Zhu, Jian, Sun, Ruping, Sun, Kaiqiang, Yan, Chen, Jiang, Jialin, Kong, Fanqi, Shi, Jiangang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149406/
https://www.ncbi.nlm.nih.gov/pubmed/37099926
http://dx.doi.org/10.1016/j.redox.2023.102707