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UTP11 deficiency suppresses cancer development via nucleolar stress and ferroptosis

The eukaryotic ribosome is essential for cancer cell survival. Perturbation of ribosome biogenesis induces nucleolar stress or ribosomal stress, which restrains cancer growth, as rapidly proliferating cancer cells need more active ribosome biogenesis. In this study, we found that UTP11 plays an impo...

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Detalles Bibliográficos
Autores principales: Gan, Yu, Deng, Jun, Hao, Qian, Huang, Yingdan, Han, Tao, Xu, Jin-Guo, Zhao, Min, Yao, Litong, Xu, Yingying, Xiong, Jianping, Lu, Hua, Wang, Chunmeng, Chen, Jiaxiang, Zhou, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149416/
https://www.ncbi.nlm.nih.gov/pubmed/37087976
http://dx.doi.org/10.1016/j.redox.2023.102705