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Analysis of complex drugs by comprehensive two-dimensional gas chromatography and high-resolution mass spectrometry: detailed chemical description of the active pharmaceutical ingredient sodium bituminosulfonate and its process intermediates

The European pharmacopeia provides analytical methods for the chemical characterization of active pharmaceutical ingredients (APIs). However, the complexity of some APIs exceeds the limitations of the currently prevailing physicochemical methods. Sodium bituminosulfonate (SBS) is described by the co...

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Detalles Bibliográficos
Autores principales: Schwalb, Lukas, Tiemann, Ole, Käfer, Uwe, Gröger, Thomas, Rüger, Christopher Paul, Gayko, Guido, Zimmermann, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149445/
https://www.ncbi.nlm.nih.gov/pubmed/36401638
http://dx.doi.org/10.1007/s00216-022-04393-w