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Analysis of complex drugs by comprehensive two-dimensional gas chromatography and high-resolution mass spectrometry: detailed chemical description of the active pharmaceutical ingredient sodium bituminosulfonate and its process intermediates
The European pharmacopeia provides analytical methods for the chemical characterization of active pharmaceutical ingredients (APIs). However, the complexity of some APIs exceeds the limitations of the currently prevailing physicochemical methods. Sodium bituminosulfonate (SBS) is described by the co...
Autores principales: | Schwalb, Lukas, Tiemann, Ole, Käfer, Uwe, Gröger, Thomas, Rüger, Christopher Paul, Gayko, Guido, Zimmermann, Ralf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149445/ https://www.ncbi.nlm.nih.gov/pubmed/36401638 http://dx.doi.org/10.1007/s00216-022-04393-w |
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