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ZD6474 attenuates TGF-β1-induced fibrosis in human Tenon fibroblasts and inhibits neovascularization via AKT-mTOR signaling pathway

PURPOSE: To investigate the anti-fibrotic effect of ZD6474 (a novel inhibitor of VEGF and EGF) in TGF-β1 stimulated human Tenon’s capsule fibroblasts (HTFs) and the anti-angiogenetic role in HUVECs, compared to that of mitomycin C (MMC). METHODS: The effects of ZD6474 on cell proliferation or migrat...

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Detalles Bibliográficos
Autores principales:	Liu, Wenting, Chen, Yaying, Song, Xiangyuan, Xue, Yiwen, Zhang, Yuyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2022
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149462/ https://www.ncbi.nlm.nih.gov/pubmed/36227401 http://dx.doi.org/10.1007/s10792-022-02548-3

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