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Climbing behavior by mice as an endpoint for preclinical assessment of drug effects in the absence and presence of pain

This study evaluated climbing in mice as a tool to assess the expression and treatment of pain-related behavioral depression in male and female ICR mice. Mice were videotaped during 10-min sessions in a vertical plexiglass cylinder with wire mesh walls, and “Time Climbing” was scored by observers bl...

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Detalles Bibliográficos
Autores principales: Santos, Edna J., Giddings, Arianna N., Kandil, Farah A., Negus, S. Stevens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149664/
https://www.ncbi.nlm.nih.gov/pubmed/37139343
http://dx.doi.org/10.3389/fpain.2023.1150236

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