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The burden of skin and subcutaneous diseases: findings from the global burden of disease study 2019

BACKGROUND: The small number of existing integrative studies on the global distribution and burden of all types of skin and subcutaneous diseases hinders relevant comparisons. OBJECTIVE: This study aimed to determine the latest distribution, epidemiological differences, and factors potentially influ...

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Autores principales: Yakupu, Aobuliaximu, Aimaier, Rehanguli, Yuan, Bo, Chen, Bin, Cheng, Jia, Zhao, Yaohua, Peng, Yinbo, Dong, Jiaoyun, Lu, Shuliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149786/
https://www.ncbi.nlm.nih.gov/pubmed/37139398
http://dx.doi.org/10.3389/fpubh.2023.1145513
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author Yakupu, Aobuliaximu
Aimaier, Rehanguli
Yuan, Bo
Chen, Bin
Cheng, Jia
Zhao, Yaohua
Peng, Yinbo
Dong, Jiaoyun
Lu, Shuliang
author_facet Yakupu, Aobuliaximu
Aimaier, Rehanguli
Yuan, Bo
Chen, Bin
Cheng, Jia
Zhao, Yaohua
Peng, Yinbo
Dong, Jiaoyun
Lu, Shuliang
author_sort Yakupu, Aobuliaximu
collection PubMed
description BACKGROUND: The small number of existing integrative studies on the global distribution and burden of all types of skin and subcutaneous diseases hinders relevant comparisons. OBJECTIVE: This study aimed to determine the latest distribution, epidemiological differences, and factors potentially influencing each skin and subcutaneous disease and the policy implications. METHODS: Data on the skin and subcutaneous diseases were obtained from the Global Burden of Disease Study 2019. The incidence, disability-adjusted life years (DALYs), and deaths due to skin and subcutaneous diseases in 204 countries and regions from 1990 to 2019 were analyzed and stratified by sex, age, geographical location, and sociodemographic index (SDI). The annual age-standardized rate of change in the incidence was obtained to evaluate temporal trends. RESULTS: Of 4,859,267,654 (95% uncertainty interval [UI], 4,680,693,440–5,060,498,767) new skin and subcutaneous disease cases that were identified, most were fungal (34.0%) and bacterial (23.0%) skin diseases, which accounted for 98,522 (95% UI 75,116–123,949) deaths. The burden of skin and subcutaneous diseases measured in DALYs was 42,883,695.48 (95%UI, 28,626,691.71-63,438,210.22) in 2019, 5.26% of which were years of life lost, and 94.74% of which were years lived with disability. The highest number of new cases and deaths from skin and subcutaneous diseases was in South Asia. Globally, most new cases were in the 0–4-year age group, with skin and subcutaneous disease incidence slightly higher in men than in women. CONCLUSION: Fungal infections are major contributors to skin and subcutaneous diseases worldwide. Low–middle SDI states had the highest burden of skin and subcutaneous diseases, and this burden has increased globally. Targeted and effective management strategies based on the distribution characteristics of each country are, thus, required to reduce the burden of skin and subcutaneous diseases.
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spelling pubmed-101497862023-05-02 The burden of skin and subcutaneous diseases: findings from the global burden of disease study 2019 Yakupu, Aobuliaximu Aimaier, Rehanguli Yuan, Bo Chen, Bin Cheng, Jia Zhao, Yaohua Peng, Yinbo Dong, Jiaoyun Lu, Shuliang Front Public Health Public Health BACKGROUND: The small number of existing integrative studies on the global distribution and burden of all types of skin and subcutaneous diseases hinders relevant comparisons. OBJECTIVE: This study aimed to determine the latest distribution, epidemiological differences, and factors potentially influencing each skin and subcutaneous disease and the policy implications. METHODS: Data on the skin and subcutaneous diseases were obtained from the Global Burden of Disease Study 2019. The incidence, disability-adjusted life years (DALYs), and deaths due to skin and subcutaneous diseases in 204 countries and regions from 1990 to 2019 were analyzed and stratified by sex, age, geographical location, and sociodemographic index (SDI). The annual age-standardized rate of change in the incidence was obtained to evaluate temporal trends. RESULTS: Of 4,859,267,654 (95% uncertainty interval [UI], 4,680,693,440–5,060,498,767) new skin and subcutaneous disease cases that were identified, most were fungal (34.0%) and bacterial (23.0%) skin diseases, which accounted for 98,522 (95% UI 75,116–123,949) deaths. The burden of skin and subcutaneous diseases measured in DALYs was 42,883,695.48 (95%UI, 28,626,691.71-63,438,210.22) in 2019, 5.26% of which were years of life lost, and 94.74% of which were years lived with disability. The highest number of new cases and deaths from skin and subcutaneous diseases was in South Asia. Globally, most new cases were in the 0–4-year age group, with skin and subcutaneous disease incidence slightly higher in men than in women. CONCLUSION: Fungal infections are major contributors to skin and subcutaneous diseases worldwide. Low–middle SDI states had the highest burden of skin and subcutaneous diseases, and this burden has increased globally. Targeted and effective management strategies based on the distribution characteristics of each country are, thus, required to reduce the burden of skin and subcutaneous diseases. Frontiers Media S.A. 2023-04-17 /pmc/articles/PMC10149786/ /pubmed/37139398 http://dx.doi.org/10.3389/fpubh.2023.1145513 Text en Copyright © 2023 Yakupu, Aimaier, Yuan, Chen, Cheng, Zhao, Peng, Dong and Lu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Public Health
Yakupu, Aobuliaximu
Aimaier, Rehanguli
Yuan, Bo
Chen, Bin
Cheng, Jia
Zhao, Yaohua
Peng, Yinbo
Dong, Jiaoyun
Lu, Shuliang
The burden of skin and subcutaneous diseases: findings from the global burden of disease study 2019
title The burden of skin and subcutaneous diseases: findings from the global burden of disease study 2019
title_full The burden of skin and subcutaneous diseases: findings from the global burden of disease study 2019
title_fullStr The burden of skin and subcutaneous diseases: findings from the global burden of disease study 2019
title_full_unstemmed The burden of skin and subcutaneous diseases: findings from the global burden of disease study 2019
title_short The burden of skin and subcutaneous diseases: findings from the global burden of disease study 2019
title_sort burden of skin and subcutaneous diseases: findings from the global burden of disease study 2019
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149786/
https://www.ncbi.nlm.nih.gov/pubmed/37139398
http://dx.doi.org/10.3389/fpubh.2023.1145513
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