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Using quantitative single molecule localization microscopy to optimize multivalent HER2-targeting ligands

INTRODUCTION: The progression-free survival of patients with HER2-positive metastatic breast cancer is significantly extended by a combination of two monoclonal antibodies, trastuzumab and pertuzumab, which target independent epitopes of the extracellular domain of HER2. The improved efficacy of the...

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Detalles Bibliográficos
Autores principales:	Wakefield, Devin L., Golfetto, Ottavia, Jorand, Raphael, Biswas, Sunetra, Meyer, Kassondra, Avery, Kendra N., Zer, Cindy, Cacao, Eliedonna E., Tobin, Steven J., Talisman, Ian J., Williams, John C., Jovanovic-Talisman, Tijana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149953/ https://www.ncbi.nlm.nih.gov/pubmed/37138747 http://dx.doi.org/10.3389/fmed.2023.1064242

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