Doxorubicin-conjugated siRNA lipid nanoparticles for combination cancer therapy

Evasion of apoptosis is a hallmark of cancer, attributed in part to overexpression of the anti-apoptotic protein B-cell lymphoma 2 (Bcl-2). In a variety of cancer types, including lymphoma, Bcl-2 is overexpressed. Therapeutic targeting of Bcl-2 has demonstrated efficacy in the clinic and is the subj...

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Detalles Bibliográficos
Autores principales: Butowska, Kamila, Han, Xuexiang, Gong, Ningqiang, El-Mayta, Rakan, Haley, Rebecca M., Xue, Lulu, Zhong, Wenqun, Guo, Wei, Wang, Karin, Mitchell, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150035/
https://www.ncbi.nlm.nih.gov/pubmed/37139433
http://dx.doi.org/10.1016/j.apsb.2022.07.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150035/
https://www.ncbi.nlm.nih.gov/pubmed/37139433
http://dx.doi.org/10.1016/j.apsb.2022.07.011

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