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Doxorubicin-conjugated siRNA lipid nanoparticles for combination cancer therapy
Evasion of apoptosis is a hallmark of cancer, attributed in part to overexpression of the anti-apoptotic protein B-cell lymphoma 2 (Bcl-2). In a variety of cancer types, including lymphoma, Bcl-2 is overexpressed. Therapeutic targeting of Bcl-2 has demonstrated efficacy in the clinic and is the subj...
Autores principales: | Butowska, Kamila, Han, Xuexiang, Gong, Ningqiang, El-Mayta, Rakan, Haley, Rebecca M., Xue, Lulu, Zhong, Wenqun, Guo, Wei, Wang, Karin, Mitchell, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150035/ https://www.ncbi.nlm.nih.gov/pubmed/37139433 http://dx.doi.org/10.1016/j.apsb.2022.07.011 |
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