Cholinergic dysfunction-induced insufficient activation of alpha7 nicotinic acetylcholine receptor drives the development of rheumatoid arthritis through promoting protein citrullination via the SP3/PAD4 pathway

Both cholinergic dysfunction and protein citrullination are the hallmarks of rheumatoid arthritis (RA), but the relationship between the two phenomena remains unclear. We explored whether and how cholinergic dysfunction accelerates protein citrullination and consequently drives the development of RA...

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Detalles Bibliográficos
Autores principales: Lv, Changjun, Sun, Minghui, Guo, Yilei, Xia, Wenxin, Qiao, Simiao, Tao, Yu, Fang, Yulai, Zhang, Qin, Zhu, Yanrong, Yalikun, Yusufu, Xia, Yufeng, Wei, Zhifeng, Dai, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150100/
https://www.ncbi.nlm.nih.gov/pubmed/37139415
http://dx.doi.org/10.1016/j.apsb.2023.01.016

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